Publications

Journal Articles:

Cox, D., Czerniawski, J., Ree, F., & Otto, T. (2013). Timecourse of dorsal and ventral hippocampal involvement in the expression of trace fear conditioning. Neurobiology of Learning and Memory, 106, 316-323. DOI: 10.1016/j.nlm.2013.05.009. Full Text 

Chia, C., & Otto, T. (2013). Hippocampal Arc (Arg3.1) expression is induced by memory recall and required for memory reconsolidation in trace fear conditioning. Neurobiology of Learning & Memory, 106, 48-55. DOI: 10.1016/j.nlm.2013.06.021. Full Text

Wass, C., Pizzo, A., Sauce, B., Kawasumi, Y., Sturzoi, T., Ree, F., & Otto, T., Matzel, L.D. (2013). Dopamine D1 sensitivity in the prefrontal cortex predicts general cognitive abilities and is a target for working memory training. Learning & Memory, 20, 617-627.  Full Text

Czerniawski, J., Ree, F., Chia, C., & Otto, T. (2012). Dorsal vs. ventral hippocampal contributions to trace and contextual conditioning: Differential effects of regionally selective NMDA receptor antagonism on acquisition and expression. Hippocampus, 22, 1258-1535. Full Text

Czerniawski, J., Ree, F., Chia, C. Ramamoorthi, K., Kumata, Y, & Otto, T. (2011). The importance of having Arc: Expression of the immediate early gene Arc is required for hippocampus-dependent fear conditioning and blocked by NMDA receptor antagonism. Journal of Neuroscience, 31, 11200-11207. Full Text

Ramamoorthi, K., Fropf, R., Fitzmaurice, H.L., McKinney, R.M., Belfort, G.M., Neve, R.L., Otto, T., & Lin, Y. (2011). Npas4 regulates a transcriptional program in CA3 required for contextual memory formation. Science, 334, 1669-1675. Full Text

Parsons, T.C., & Otto, T. (2010). Time-limited involvement of dorsal hippocampus in unimodal discriminative contextual conditioning. Neurobiology of Learning and Memory, 94, 481-487.  Full Text

Czerniawski, J., Yoon, T., & Otto, T. (2009).  Dissociating space and trace in dorsal and ventral hippocampus. Hippocampus, 19, 20-32. Full Text

Parsons, T., & Otto, T. (2008).Temporary inactivation of dorsal hippocampus attenuates explicitly nonspatial, unimodal, contextual fear conditioning. Neurobiology of Learning and Memory, 90, 261–268.  Full Text 

Yoon, T., & Otto, T. (2007). Differential contributions of dorsal vs. ventral hippocampus to auditory trace fear conditioning. Neurobiology of Learning and Memory, 87, 464-475.  Full Text

Otto, T., & Poon, P. (2006). Dorsal hippocampal contributions to unimodal contextual conditioning. Journal of Neuroscience, 26, 6603-6609. Full Text

Nicot, A., Otto, T., Brabet, P.,&  DiCicco-Bloom, E.M. (2004). Altered social behavior in pituitary adenylate cyclase-activating polypeptide Type-I receptor-deficient mice. Journal of Neuroscience, 24, 8786-8795.

Cousens, G., & Otto, T. (2003). Contributions of orbitofrontal cortex and basolateral amygdaloid complex to olfactory discrimination learning with auditory secondary reinforcement. Integrative Physiological & Behavioral Science, 38, 272-294.

Herzog, C.D., & Otto, T. (2002).Administration of transforming growth factor alpha enhances anatomical and behavioral recovery following olfactory nerve transection. Neuroscience, 113, 569-580.

Schettino, L.F. , & Otto, T. (2001). Patterns of Fos expression in the amygdala and ventral perirhinal cortex induced by training in an olfactory fear conditioning paradigm. Behavioral Neuroscience, 115(6), 1257-1272.

Otto, T., & Giardino, N. (2001). Pavlovian conditioning of emotional responses to olfactory and contextual stimuli: A potential model for the development and expression of chemical intolerance.  Annals of the New York Academy of Sciences, 933, 291-309.

Otto, T., Cousens, G., & Herzog, C.D. (2000). Behavioral and neuropsychological foundations of olfactory  fear conditioning. Behavioural Brain Research, 110, 119-128.

Herzog, C.D., & Otto, T. (1999). Regeneration of olfactory receptor neurons following chemical lesion: Time course and enhancement with growth factor administration. Brain Research, 849, 155-161. Full Text (pdf format)

Cousens, G., & Otto, T. (1998). Both pre- and post-training lesions of the basolateral amygdala abolish the expression of olfactory and contextual fear conditioning. Behavioral Neuroscience, 112, 1092-1103.

Herzog, C.D., & Otto, T. (1998). Contributions of anterior perirhinal cortex to olfactory and contextual fear conditioning. Neuroreport, 9, 1855-1859.

Flaherty, C.F., Coppotelli, C., Hsu, D., & Otto, T. (1998). Excitotoxic lesions of the hippocampus disrupt instrumental but not consummatory contrast. Behavioural Brain Research, 93, 1-9.

Cousens, G., & Otto, T. (1998). Long-term potentiation and its transient suppression in the rhinal cortices induced by theta-related stimulation of hippocampal field CA1. Brain Research, 780, 95-101.  Full Text (pdf format)

Otto, T., & Garruto, D. (1997). Rhinal cortical lesions impair simultaneous olfactory discrimination learning in rats. Behavioral Neuroscience, 111, 1-5.

Otto, T., Cousens, G., & Rajewski, K. (1997). Odor-guided fear conditioning. I. Acquisition, retention, and latent inhibition. Behavioral Neuroscience, 111, 1257-1264.

Herzog, C.D., & Otto, T. (1997). Odor-guided fear conditioning. II. Lesions of anterior perirhinal cortex disrupt fear conditioned to the explicit CS but not to the training context. Behavioral Neuroscience, 111, 1265-1274.

Otto, T., Wolf, D., & Walsh, T. (1997). Combined lesions of perirhinal and entorhinal cortex impair rats’ performance in two versions of the spatially-guided radial arm maze. Neurobiology of Learning and Memory, 68, 21-31.

Young, B.J., Otto, T., Fox, G., & Eichenbaum, H. (1997). Memory representation in the parahippocampal region. Journal of Neuroscience, 17, 5183-5195.

Eichenbaum, H., Otto, T., & Cohen, N.J. (1996). The hippocampal system: Dissociating its functional components and recombining them in the service of declarative memory. Behavioral and Brain Sciences, 19, 762-776.

Zyzak, D.R., Otto, T., Eichenbaum, H., & Gallagher, M. (1995). Cognitive decline associated with normal aging in rats: A neuropsychological approach. Learning & Memory, 2, 1-16.

Nagahara, A. H., Otto, T., & Gallagher, M. (1995). Entorhinal lesions impair performance in two versions of place learning in the Morris water maze. Behavioral Neuroscience 109, 3-9.

Eichenbaum, H., Otto, T., & Cohen, N.J. (1994). Two functional components of the hippocampal memory system. Behavioral and Brain Sciences, 17(3),449-517.

Otto, T., & Eichenbaum, H. (1992). Neuronal activity in the hippocampus during delayed non-match to sample performance in rats: Evidence for hippocampal processing in recognition memory. Hippocampus, 2(3), 324-334.

Otto, T., & Eichenbaum, H. (1992). Complementary roles of orbital prefrontal cortex and the perirhinal/entorhinal cortices in an odor-guided delayed non-matching to sample task. Behavioral Neuroscience, 106, 763-775.

Eichenbaum, H., Otto, T.  & Cohen,  N.J. (1992). The Hippocampus – What Does It Do? Behavioral and Neural Biology, 57, 1-35.

Otto, T., Schottler, F., Staubli, U., Eichenbaum, H., & Lynch, G. (1991). The hippocampus and olfactory discrimination learning: Effects of entorhinal cortex lesions on odor memory in a successive-cue, go, no-go task. Behavioral Neuroscience, 105, 111-119.

Otto, T., Eichenbaum, H. Wiener, S.I., & Wible, C.G. (1991). Learning-related patterns of CA1 spike trains parallel stimulation parameters optimal for inducing hippocampal long-term potentiation. Hippocampus 1, 181-192.

McCollum, J., Larson, J., Otto, T., Schottler, F., Granger, R.,& Lynch, G. (1991). Short-latency single unit processing in olfactory cortex. Journal of Cognitive Neuroscience, 3, 293-299.

Granger, R., Staubli, U., Powers, H., Otto, T., Ambros-Ingerson, J., & Lynch, G. (1991). Behavioral tests of a prediction from a cortical network simulation. Psychological Science, 2, 116-118.

Mair, R.G., Otto, T.A., Knoth, R., Rabchenuk, S., & Langlais, P. (1991). An analysis of aversively conditioned learning and memory in rats recovered from pyrithiamine-induced thiamine deficiency. Behavioral Neuroscience, 105, 351-359.

Fuld, K., Otto, T.A., & Slade, C.W. (1986). The spectral responsivity of the white-black channel. Journal of the Optical Society of America, A, 3, 1182-1188.

Fuld, K., & Otto, T.A. (1985). Colors of monochromatic lights that vary in contrast-induced brightness. Journal of the Optical Society of America, A, 2, 76-83.

Chapters and Commentaries:

Otto, T. (1997). Long-term potentiation in the hippocampus of the anesthetized rat. In C.A. Paul, B. Beltz, & J. Berger-Sweeney (Eds.), Discovering Neurons.Cold Spring Harbor Laboratory Press.

Otto, T., & Eichenbaum, H. (1994). The hippocampus, long-term potentiation, and memory: Enhancing the connection. In M. Baudry & J. Davis (Eds.), Long-Term Potentiation, Vol.2. Cambridge: MIT Press (pp 305-334).

Otto, T., & Eichenbaum, H. (1992). Toward a comprehensive account of hippocampal function: Studies of olfactory learning permit an integration of data across multiple levels of neurobiological analysis. In Neuropsychology of Memory, N. Butters & L.R. Squire (Eds.). New York: Guilford (pp. 415-428).

Otto, T., & Eichenbaum, H. (1992). Olfactory learning and memory in the rat: A “model system” for studies of the neurobiology of memory. In The Science of Olfaction, K. Chobor& M. Serby, (Eds.). New York: Springer-Verlag (pp. 213-244).

Eichenbaum, H., & Otto, T. (1993). Odor-guided learning and memory in rats: Is it ‘special’? Trends in Neurosciences, 16, 22-24.

Eichenbaum, H., & Otto, T. (1993). Where perception meets memory: functional coding in the hippocampus. In Brain Mechanisms of Perception and Memory: From Neuron to Behavior, T. Ono, L.R. Squire, D. Perret, & M.E. Raichle (Eds.).

Eichenbaum, H., & Otto, T. (1993). LTP and memory: Can we enhance the connection?. Trends in Neurosciences, 16, 163-164.

Eichenbaum, H., & Otto, T. (1992). The hippocampus and the sense of smell. In Chemical Signals in Vertebrates VI, R. Doty (Ed.), Plenum Press, NY. (pp. 67-77).

Eichenbaum, H., Otto, T., Wible, C.,& Piper, J. (1991). Building a model of the hippocampus in olfaction and memory. In Olfaction as a Model for Computational Neuroscience, J. Davis & H. Eichenbaum, (Eds.) Cambridge: MIT Press (pp. 167-210).

Eichenbaum, H., Cohen, N.J., Otto, T., & Wible, C. (1991). Memory representation in the hippocampus: Functional domain and functional organization. In Memory: Organization and Locus of Change, L.R. Squire, G. Lynch, N.M. Weinberger,& J.L. McGaugh, (Eds). Oxford University Press.

Eichenbaum, H., Cohen, N.J., Otto, T., & Wible, C. (1991) A snapshot without the album. Brain Research Reviews, 16, 209-220.